FLUIDNATEK LE-100: Advanced platform for R&D electrospinning and scale-up

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Fluidnatek LE-100

The Fluidnatek LE-100 is a highly versatile electrospinning and electrospraying machine for advanced R&D, process scale up, and small-scale production of electrospun nanofibers. It’s a multi-purpose platform for different applications, though designed and engineered from its root to meet highly demanding biomedical applications.

It combines multiple spinning head configurations, needle-based and needle-less technologies, strong environmental control capabilities, advanced syringe pump systems for precise solution dosing, automated X/Y/Z motion control, rotating collectors and roll-to-roll collector, real-time process monitoring, and in-line thickness metrology to support demanding applications from flat materials on roll-to-roll collectors to coatings on implantable medical devices.

Designed to guarantee reproducibility, consistency, repeatability, system-to-system matching and scale-up readiness, along with a high flexibility at operation, the Fluidnatek LE-100 is ideal for laboratories and industries working with fibers, particles, and complex multi-material processes, for whom a scalable, stable, and fully under control process is a must.

This electrospinning machine is ideal for advanced R&D, process scaling, and small-scale production, offering exceptional versatility across the development of electrospun nanofibers and related materials.

It supports various collector types, including static flat plate, rotating collectors such as drums, mandrels and discs, electrospun fiber-yarn collector, as well as roll-to-roll collector for semi-continuous production of flat electrospun sheets and membranes.

Environmental control is critical to ensuring consistent and reproducible production, since all materials are sensitive to environmental conditions, especially to humidity. The Fluidnatek LE-100 can be fitted with Environmental Control Unit – ECU or Drying-Heating Unit – DHU, to allow temperature and humidity regulation, helping stabilize the spinning environment and as a result to dramatically improve reproducibility. The ECU unit delivers heating-cooling and drying-humidifying, all degrees of freedom, with ranges of 18-45ºC for temperature and 10-80% for relative humidity (psychrometric chart available).

Environmental control is critical to ensuring consistent and reproducible production. The Fluidnatek LE-100 can be fitted with an Environmental Control Unit (ECU) capable of heating-cooling and drying-humidifying, with ranges of 18-45ºC for temperature and 10-80% for relative humidity (see psychrometric chart).

A multitude of advanced tools: tools geared towards Industry 4.0, needle-based & needle-less technology available, real-time data collection tools for process and equipment variables with configurable dashboard and alarm management, advanced process automation, electro-blow spinning ability, dual spinning, dummy collector for process stabilization prior to deposition, and more.

The Fluidnatek LE-100 is so adaptable that it offers a wide variety of spinning arrangements inside its large experimental chamber. Possibility of automated movement on X-Y-Z axes and simultaneous deposition of electrospun nanofibers of 2-3 different solutions. X, Y, and Z axis automation expands the usable processing area, supports homogeneous deposition, and makes it easier to adapt the machine to wider samples, coatings, and more complex motion profiles..

Fluidnatek LE-50 G2 technical specifications for lab-scale electrospinning and electrospraying
FeatureFluidnatek LE-100 SpecificationWhy It Matters
Equipment TypeAdvanced laboratory electrospinning and electrospraying platform for R&D, process scale up, and small-scale production of electrospun nanofibers and electrosprayed particlesThe modular configuration allows for the seamless upgrade and integration of additional items and features, at any time. Thanks to its great upgradability, researchers benefit from a highly adaptable and user-friendly platform. Importantly, researchers can cover the phases of proof-of-concept, process optimization, process scale up to demonstrate the process is scalable, and even the production of small batches of materials (handsheets or material rolls).
Operating ModesR&D and small-batch production of fibers and/or particlesProvides flexibility for both early-stage development and small-scale manufacturing workflows.
Batch Volume1 mL to 180 mL with 3 syringe pumps; up to 560 mL with 2 high-pressure twin-channel syringe pumpsEnables scalable batch sizes depending on the configuration and process requirements.
Run Time5 min to 24 h (or longer), depending on the polymer solutionAllows short exploratory runs and extended production cycles within the same platform.
Fiber Diameter RangeTypical fiber/particle diameters: 20 nm to 10 µm, dependent on material, formulation, and process parametersSupports a wide range of fiber and particle sizes for different applications.
Environmental ControlOptional ECU: 18°C to 45°C (±1°C) and 10% to 80% RH (±3%), depending on temperatureHelps maintain stable spinning conditions and improves reproducibility across runs.
ThroughputUp to 20 emitters in a single linear multi-emitter spinning head; up to 40 emitters with two heads on the articulated mounting armEnables higher deposition rates and supports scale-up and wider-area processing.
Footprint896 mm width × 1240 mm depth × 1950 mm height; weight ~350-400 kgSuitable for advanced laboratory installations that need a substantial but controlled footprint.
Safety StandardsCE compliant, fulfilling the corresponding EU DirectivesSupports safe operation in laboratory and regulated environments.
Data IntegrationData logging and export, High-Definition Process Data Hub, recipe database, audit trail, batch controlSupports traceability, process repeatability, and validated workflows.
Process AutomationProgrammable sequential multi-step recipe function, remote visualization & commanding, automated spinning distance, X/Y axis scanningImproves process consistency and enables more advanced automated workflows.
ComplianceCE compliant and independently verifiedtion, UV-C germicidal lampsThe Fluidnatek LE-100 electrospinning machine complies with the applicable EU Directives for safe operation, including the Machinery Directive, the EMC Directive (electromagnetic compatibility), and the Low Voltage Directive (electrical safety). It reinforces reliability across laboratory setups, educational settings, and professional or industrial facilities.

FLUIDNATEK LE-100

technical information

See all the features in our information sheet.

Fluidnatek LE-100 platform made of stainless steel

Cabinet of the Fluidnatek LE-100 machine